What Are the Complications of Nephrotic Syndrome?

What Are the Complications of Nephrotic Syndrome? Nephroptic syndrome is caused by many factors which has the characteristics of large amount of proteinuria, hyperlipemia, hypoalbuminemia, and swelling. Here are the detailed complications of nephritic syndrome:

1. Infection.

Due to massive immune globulin losing in urine, the plasma proteins decreases which will affect formation of the antibody. The application of adrenocortical hormone and cytotoxic drugs can decline the body resistance. It easily induces infections of skin, primary peritonitis, respiratory tract, urinary system and even septicemia.

2. Coronary disease.

The patients are usually with hyperlipemia and hypercoagulable state, which easily trigger the coronary disease. It is reported that the incident rate of myocardial infarction for the patients is eight times higher than those of common people.

3. Formation of thrombus.

The patients are easily attacked by thrombus. Especially for the morbidity of membrane kidney disease, it can even reach 25%-40%. The leading causes include swelling, little activities, venous stasis, high blood fat, increase of glutinousness due to hemoconcentration, over high content of fibrinogen, etc.

4. Acute kidney failure.

The patients easily fall into the state of hypovolemia, and hypercoagulable and manifest vomiting, diarrhea, caused by massive proteinuria, hypoproteinemia, and hyperlipemia. When they take medicines for lowering blood pressure and diuresis, the perfusion of the blood will slash in a sudden, which will reduce the filtration rate of glomeruli and lead to acute renal failure at last. Furthermore, renal interstitial swelling and cast formed by protein concentration blocking kidney tubules can also trigger acute kidney failure.

5. Disorder of electrolyte and metabolism.

Taking diuretic and improperly limiting salt intake for a long time can induce hyponatremia. Large amount of urine volume is the result of using adrenocortical hormone and much diuretic, in this condition, hypokalemia easily occurs due to no prompt supplying for the potassium.

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