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What are the Factors of the Diabetic Nephropathy?

Diabetic Nephropathy is the most common cause of kidney failure. But I think many people know a little about the reason of diabetic nephropathy. What on earth causes Diabetic Nephropathy? This question has been asked many times. To know the causes is helpful for us to put forward treatment plans and preventive measures. While, there are some corresponding factors:

Diabetic Nephropathy is a kidney disease which may be caused diabetes. Diabetes is characterized by high blood sugar. It is well known that kidney is surrounded by many tiny blood vessels, which may be damaged exposed to high blood sugar for a long time. As a result, there is not enough oxygen and nutrients transported to kidney. Kidney failure occurs due to ischemia and anoxia.

Of course, not everyone with diabetes develops kidney disease. People with diabetes are susceptible to developing Diabetic Nephropathy. The factors are list as followings:

1. Renal homodynamic abnormalities. It plays a key role in diabetic nephropathy and may be the initiating factors.

2. Genetic factors. Some patients who control the blood sugar very well for a long time also can have the diabetic nephropathy. Glucose transporters are mainly glucose transporter on glomerular mesangial cells. Recent studies have found that people with diabetes is easy to lead to the kidney disease in the end.

3. High blood pressure. It has no direct relation with the diabetic nephropathy, but after the blood pressure become high, it can accelerate the progress of diabetic nephropathy, the deterioration of renal function and increase the excretion of urine albumin.

4. Hyperglycemia. Diabetic nephropathy is closely related to the high blood sugar, if the blood sugar can not be controlled very well, it can accelerate the development of diabetic nephropathy. Hyperglycemia can lead to membrane cell hyperplasia, extracellular matrix, mesangial expansion and glomerular basement membrane thickening, etc.

Now you have a general knowledge about the factors of Diabetic Nephropathy, so you should try to bring these risk factors under control. Only in this way, you can avoid Diabetic Nephropathy and reduce the damage to kidneys.

If you have any other questions about kidney disease, please contact our online doctors or leave us a message. Good luck to you.

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