The Cause of Polyuria and Thirst in FSGS

Generally speaking, when people are attacked by FSGS, with the development of the disease, patients will excrete less and less urine. But some patients has the opposite symptom, polyuria which is accompanied with thirst. Why patients suffer that? Today let us have a study about the cause of polyuria and thirst in FSGS.

There are two main components in urine: the water as solvent and all kinds of metabolism waters as solute. When people are attacked by FSGS, the glomerulus functions also be injured, so the toxins in body can not be excreted out effectively and stay in body. But the molecular weight of water is small and it is enter into glomerular capsule through the glomerular filtration membrane, and the water filtration volume per day can reach 150L, and we call the fluid as crude urine.

Most of the crude urine can be reabsorbed according to the human body needs when they get through the renal tubule and collecting duct. The excreted urine is about 400-3000ml per day. But when the glomerulus and kidney tubules are damaged at the same time, the reabsorption function is influenced and FSGS patients will suffer polyuria. In addition, with the water increase in urine, the concentration of urine is low, so the toxins have not been excreted effectively. Polyuria dosen’t mean the excreting toxins a lot.

Sometimes, due to the polyuria, patients suffer dehydration and get thirst feelings. For FSGS patients, dehydration can decrease the blood perfusion in kidney, leading to more serious renal insufficient.

All in all, FSGS also can lead to polyuria and thirst which are easy disregardful by patients for they always think that patients with kidney function decline would never suffer polyuria. So FSGS patients with polyuria also need pay more attention to their physical condition and have a timely treatment in case missing the best time for treatment. And if you want to know more informationabout polyuria and thirst in FSGS or other symptoms, you can contact our online doctors, leave us messages or send email to kidneyhospitalabroad@hotmail.com, we will reply you within 24 hours.